Welcome to the
​De Bo group website

Our group is based in the Department of Chemistry of the University of Manchester. Our research focuses on the application of mechanical force in new synthetic process and on the creation of new mechanoresponsive molecular devices and materials.

Join us

Check our Vacancies here.

Highlighted Research

Force-controlled release of small molecules with a rotaxane actuator
L. Chen, R. Nixon, and G. De Bo*
Nature 2024, 628, 320-325.

Latest Research

Pushing vs Pulling: The Unique Geometry of Mechanophore Activation in a Rotaxane Force Actuator
L. Chen and G. De Bo*
J. Am. Chem. Soc. 2024, 146, 16381–16384.
Mechanochemical Generation of Aryne
Q. Cheng and G. De Bo*
Chem. Sci. 2024, 15, 13181–13184